GH Provocative Test in Diagnosis of GH deficiency in Childhood, Can We Trust on Them?
نویسندگان
چکیده
منابع مشابه
Which patients do not require a GH stimulation test for the diagnosis of adult GH deficiency?
Adult GH deficiency (GHD) is currently diagnosed in patients with either a history of childhood-onset GHD or acquired hypothalamic-pituitary disease by GH stimulation testing. However, GH stimulation tests are invasive, time consuming, and associated with side effects. Based on preliminary analyses of patients enrolled in the U.S. Hypopituitary Control and Complications Study (HypoCCS), we prop...
متن کاملGH deficiency in adults.
Until the last decade, the diagnosis of GH deficiency (GHD) in adults was only considered as a marker of hypothalamo-pituitary disease. GHD in adults is now recognized as a specific clinical syndrome associated with a cluster of cardiovascular risk factors such as altered body composition with increased body fat, insulin resistance, adverse lipid profile, reduced physical performance, reduced b...
متن کاملDiagnosis of growth hormone (GH) deficiency: comparison of pituitary stalk interruption syndrome and transient GH deficiency
BACKGROUND Most patients with childhood non-organic growth hormone (GH) deficiency (GHD) produce a normal GH peak as young adults. Our objectives were to better define this transient GHD and evaluate the factors influencing the growth response of patients with pituitary stalk interruption syndrome (PSIS). METHODS We studied 72 prepubertal patients with a GH peak < 6.7 ng/ml after 2 stimulatio...
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Correspondence to: Dr. Tetsuo NISHIKAWA, Department of Medicine, Yokohama Rosai Hospital, 3211 Kozukue-cho, Kohoku-ku, Yokohama City, Kanagawa 222, Japan
متن کاملComparison between insulin-induced hypoglycemia and growth hormone (GH)-releasing hormone + arginine as provocative tests for the diagnosis of GH deficiency in adults.
There is now wide consensus that, within an appropriate clinical context, GH deficiency (GHD) in adults must be shown biochemically by provocative testing of GH secretion and that appropriate cut-off limits have to be defined for each provocative test. Insulin-induced hypoglycemia (ITT) is indicated as the test of choice, and severe GHD, to be treated with recombinant human GH replacement, is d...
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ژورنال
عنوان ژورنال: International Journal of Pediatrics, Neonatology and Primary Care
سال: 2019
ISSN: 2689-162X
DOI: 10.18689/ijpn-1000106